"Everyone wants to be Cary Grant. Even I want to be Cary Grant." - Cary Grant
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An image search referral I got: "she-male d&d" (sans quotes).
Would that be a gender or a class? If the latter...
Class: She-Male
Alignment: Any non-Lawful. Chaotic characters get a 5% XP bonus.
Primary Attributes: Dex (dodging the police), Cha (duh)
Class Skills: Bluff; Disguise; Knowledge: Other gender; Perform
Class Bonus: Aura of Gender Otherness: Cispersons roll a fear check when within 60". Any cispersons failing their fear check will take -5 Wis & -5 Con penalties for 10 turns as they question their cisperson privilege and gender identity.
Class Weapon Restrictions: Stiletto Heel, Leather Thong +3, Unarmed Combat: Catty Bitching
Feats: Breast Revealing; Heel Throwing; Suppress Adam's Apple; Hiding Penile Bulge; Speak in Falsetto; Makeup Shield (+5 AC)
Prestige Classes: Changi Village Bapok; Bugis Duck; Iron Lady; Kathoey; Hijra; Mukhannathun.
Once in a She-Male's career, he can undergo an Operation, which will effect the following attribute changes: -1 Str, -1 Con, +3 Cha. This process is irreversible. The She-Male also gains the feat: False Vagina, which adds +3 DC to spot checks for gender.
(with contributions from nw.t)